Concerning Trachoma

Trachoma

Trachoma.

Trachoma is the most common infectious cause of blindness. It is caused by ocular serovars of Chlamydia trachomatis. Transmission is favoured in poor communities, where crowding is common and access to water and sanitation inadequate. Repeated reinfection over many years causes dense scarring of the upper eyelid. The resultant inversion of the lashes abrades the eyeball, and the abrasion leads ...

Expression of MHC class II antigens by conjunctival epithelial cells in trachoma: implications concerning the pathogenesis of blinding disease.

In an attempt to understand the pathogenesis of corneal changes and conjunctival scarring in trachoma, which are responsible for blindness in some 7 million people worldwide, the surface expression of major histocompatibility complex class II antigens on conjunctival epithelial cells was sought in patients with different clinical features of the disease. Class II expression was significantly as...

Trachoma in the Pacific Islands: evidence from Trachoma Rapid Assessment.

AIMS To establish the presence or absence of trachoma in the Pacific Island region. METHODS Trachoma Rapid Assessment methodology was used in Kiribati, Nauru, Vanuatu, Solomon Islands and Fiji. Advised by key informants, high-risk communities were chosen from each country. All available children aged 1-9 years and adults > or = 40 years were examined. RESULTS A total of 903 adults > or = 40...

Epidemiology of Trachoma: A Report by Sitapur Trachoma Study Group

Trachoma is the most common cause of infectious blindness worldwide and it affects more than 150 million people. Despite of various control programs, it still persists and lead to significant ocular morbidity. We have done Prospective clinical epidemiological study conducted at Regional Institute of Ophthalmology (RIO) & Sitapur Eye Hospital (SHE), Sitapur, Uttar Pradesh, India. RIO & SEH is a ...